6- -2,2 bipyridine, with ruthenium carbonyls

Reduchon of carbonyls to give alcohol funchonalities is an important transformation in synthetic chemistry. Simple aldehydes and ketones can be hydrogenated under aqueous-phase catalysis. For instance, ruthenium in combination with TPPTS allows the hydrogenation of simple aliphatic aldehydes under either biphasic [52] or homogeneous [53] conditions. Thus, [Ru2(CO)4(OAc)(bipy)2][OAc] promoted the reduchon of acetone, affording 84% yield with a TOF of 133 h at 100 °C and 100 bar H2 in water in 24 h [54]. As shown in Scheme 6.5, subshtuted acetophenones were reduced with [Ir(cod) Cl]2 in the presence of a bipyridine ligand, showing >88% conversion in water at neutral pH [55]. 

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