Biosynthesis of Histones as a Genetic Problem

1) Theoretical aspect of the problem of morphogenetic repressors. If we accept that the histones possess repressor functions, the problem of their biosynthesis, like that of the synthesis of other possible specific repressors, is of considerable morphogenetic importance. Genetic repressors at the bacterial level have in fact provided a logical explanation of genetic differentiation of the cells (activity of some and passivity 

On the other hand, durit morphogenesis of hi er organisms, the concept of repressors does not provide a logical explanation of the purposive inherited automation of development, and if we assume that differences in the spectrum of active and passive genes in different tissues are associated with differences in the assortment of repressors, we are naturally faced with a question of the same order of complexity why is it that a different assortment of repressors is formed in different tissues, and what controls the purposiveness of this phenomenon in time and in connection with its localization  

In this case the region of the DNA stock controlling synthesis of repressor proteins is hundreds of times smaller than the mass of DNA controlling the synthesis of other proteins, and the illogicality of including the first and second systems in the same category of complexity thus clearly disappears, although the difficulty of 

It is obvious that before we change to the concrete language of facts when discussing these relationships, we must examine the latest information concerning biosynthesis of histones. 

2) Biosynthesis of Histones. Like the synthesis of many other nuclear proteins, the biosynthesis of histones has been studied from many different points of view. The existence of surveys of the literature on this problem (Mirsky and Osawa, 

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