Biosynthesis of Bile Acid Conjugates

The enzymic nature of the bile acid conjugation was. stated by Massza and Stolfi (1932). These authors succeeded in preparing an enzyme from 

The conjugation of free bile acids to taurine and glycine is a synthesis of an amide bond comparable to the synthesis of gluthatliione from glutamic acid, cysteine, and glycine, with the synthesis of hippuric acid from benzoic acid and glycine or with tlie synthesis of protein from amino acids. 

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