Biostability defined

Our research started some 10 years ago after the development of designed controlled release devices when we recognized that the material requirements for a drug delivery device and that of an implantable macro-immunoisolatory membrane are quite similar. For both applications the devices must be biocompatible ( bioinvisible ) and biostable, must have smooth non-clogging surfaces even after long implantation times, must allow the diffusion of desirable well-defined molecules, must have controlled pore sizes, must be sterilizable, and must have robust mechanical properties for implantation, use, and easy retrieval. 

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