Bioseparations downstream processing

Belter, P. A., E. L. Cussler, and W. Hu, Bioseparations Downstream Processing for Biotechnology. New York, NY John Wiley Sons, 1988. 

Belter, P.A. Cussler, E.L. Hu, W-S. Bioseparations Downstream Processing for Biotechnology Wiley Interscience New York, 1998. 

Belter PA, Cussler EL, Hu WS (1988) Bioseparations downstream processing for biotechnology. Wiley, New York... 

Belter, P.A., E.L. Cussler and W.-S. Hu, Bioseparations Downstream Processing in Biotechnology, Wiley-Interscience, John Wiley, New York (1988). An introduction to bioseparations. (Belter et al., 1988.)... 

After successful fermentation or enzyme reactions, desired products must be separated and purified. This final step is commonly known as downstream processing or bioseparation, which can account for up to 60 percent of the total production costs, excluding the cost of the purchased raw materials (Cliffe, 1988). 

Included here are short summaries of various oral presentations made at the Ninth Conference on Recovery of Biological Products, held on May 23-28, 1999, in Whistler, Canada. This conference has become the preeminent meeting in the field of bioseparations, and it provides exposure to the latest developments in the state-of-the-art downstream processing. Dr. S. Cramer of Rensselaer Polytechnic Institute was kind enough to cover this meeting, and his report follows. Various session titles are listed in the order of presentation. 

The remainder of this introductory chapter focuses on downstream processing and bioseparation relevant to the chapters presented in this book. Thus, the following topics are covered multiphase systems, membrane separation, centrifugation and adsorption techniques, electrophoresis, chromatography, and affinity separations. 

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