Biophysical Applications of Metal-Ligand Probes

Thrae ate numaous biophysical applications for long-life-time anisotropy probes. These include studies of all types of macromolecular assemblies. The use of long-lifetime probes in biochemistry is just banning. We have chosen to show just three representative applications studies of DMA dynamics, measurement of domam-to-domain mo- 

DMA Dynamics with Metai-Ugand Probes 

A spherical moleciile win display a single conelation time, and, in gencfal, gMadar pndeins display clos spaced conebdkio times doe to overall rotational difliision. b 

F re 20.12, Dependnoe of the aonradiatiw decay rale of I corapJcMi on the emission mexiiHum. I kK -1000 cin V Revbcd Ref. 21. 

In order to be nsefrd for anisotropy measurements, a probe most display a large fundamental anisotropy (ro). 

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