Biomedical applications of nitric oxide-releasing polyurethanes

3 Biomedical applications of nitric oxide-releasing polyurethanes 

Extracorporeal circulation (ECC) is used in a wide variety of hospital procedures including short-term hemodialysis, extracorporeal membrane oxygenation, and other 

PUs can address the surface fouling issue associated with in vivo glucose sensors, while NO plays a critical role in mediating inflammatory response in addition to 

A wound can technically be defined as a disturbance in the steady state equilibrium between the outermost skin layer (epidermis) and the inner layer (dermis). 

Nitric oxide has been shown to prevent bacterial infection, as well as thrombus formation (Langford et al., 1994 Radomski et al., 1992 Salas et al., 1994). These attributes have the potential to improve the efficacy of catheter devices. Many combinations of polymer chemistries and delivery methods of NO have been investigated (Parker et al., 2009 Tambyah, 2004 van Rooden et al., 2005 Regev-Shoshani et al., 2010 Kishikawa et al., 2013 Ren et al., 2014 Schoenfisch et al., 2000 Hamek et al., 2011). 

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