Biomarkers of Endocrine Disruption

Depledge, in Toxic Impacts of Wastes on the Aquatic Environment, ed. J. F. Tapp, S. M. Flunt 

Aruwke, F. R. Knudsen and A. Goksyor, Environ. Health Perspect., 1997, 105, 418. 

Cyprid major protein is a larval storage protein necessary for successful metamorphosis. Production of cyprid major protein was increased in the barnacle Balanus amphitrite following exposure to both nonylphenol and estradiol, suggesting that it may be a potential biomarker of estrogen exposure in invertebrates such as barnacles.  

Another potential histopathological biomarker of endocrine disruption is the development of ovotestes in the lobster Homarus americanusf 

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Develop biomarkers of endocrine disruption. F iirther evidence of endocrine disruption is required in addition to population parameters. Biochemical and histopathological biomarkers are required to identify which hormone systems are affected. 

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