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Biomarker Discovery Pathway

The process for a biomarker discovery process is very similar regardless of the type of molecule that one is looking for. Here, detailed descriptions of the challenges in the biomarker discovery pathway, which have to be kept in mind, are outlined. This section will also provide some information about how these challenges can be met by the careful researcher. [Pg.516]

Bichsel VE, Liotta LA, Petricoin EF 3rd. Cancer pro-teomics From biomarker discovery to signal pathway profiling. Cancer J 2001 7 69-78. [Pg.287]

Crockford, D.J. et al., Statistical search space reduction and two-dimensional data display approaches for UPLC-MS in biomarker discovery and pathway analysis, Anal. Chem., 78(13), 4398,2006. [Pg.330]

Bichsel, V.E., Liotta, L.A., and Petricoin, E.F., 3rd, (2001) Cancer proteomics from biomarker discovery to signal pathway profiling. Cancer J 7, 69-78. Chuaqui, R., Cole, K., Cuello, M., Silva, M., Quintana, M.E., and Emmert-Buck, M.R. (1999) Analysis of mRNA quality in freshly prepared and archival Papanicolaou samples. Acta Cytol 43, 831-6. [Pg.88]

Accurately quantifying individual identified lipid species for pathway analysis, comparably profiling the lipid samples for biomarker discovery. [Pg.13]

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