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Biologically based dose-response BBDR

Physiologically Based Pharmacokinetic (PBPK) models and Biologically Based Dose-Response (BBDR) models are finding increasing use in risk assessment... [Pg.40]

Use of a biologically based dose-response (BBDR) model that can capture multiple MOAs, which may dominate in different portions of the dose-response curve [e.g., the formaldehyde assessment by The Hamner Institutes for Health Sciences, formerly Chemical Institute of Industrial Toxicology (CUT 2009)], which has been used in regulatory settings (Conolly et al. 2004). [Pg.616]

See other pages where Biologically based dose-response BBDR is mentioned: [Pg.39]    [Pg.127]    [Pg.666]    [Pg.39]    [Pg.127]    [Pg.666]    [Pg.576]    [Pg.849]    [Pg.88]    [Pg.115]    [Pg.101]    [Pg.674]   
See also in sourсe #XX -- [ Pg.127 ]



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