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Biological-Chemical Hybrid Approaches

The use of "natural" biological materials is particularly promising if a combination of biological and synthetic structures, i e, a hybrid approach is chosen to build chemical sensor systems Again the controlled signal transduction across interfaces plays the central role in current research... [Pg.92]

Gill, I. and Ballesteros, A. (1998) Encapsulation of biologicals within silicate, siloxane, and hybrid sol-gel polymers An efficient and generic approach. Journal of the American Chemical Society, 120, 8587-8598. [Pg.108]

Despite of hybridization with biological ligands, the general strategy for optimizing protein adsorption on biomaterial surfaces relies on chemical or physicochemical modulation of surface hydrophilicity [38,39]. The common approach is surface immobilization of hydrophilic polymers like polyethylene glycol [PEG] or polysaccharides. Four categories of surface-modification pathways have been developed ... [Pg.187]

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