Biogenesis of flavonoids

The biogenesis of flavonoids in plants is well documented and known to take place by chain extension of 4-hydroxycinnamoyl-CoA (126) with malonyl CoA through the acetate pathway involving enzymes like chalcone S3mthase (86). Here, the initially formed polyketide 127 may undergo a Claisen-type condensation to form a chalcone and subsequently other flavonoids, as shown in Fig. 25. It is pertinent to... 

No studies have been carried out on the biogenesis of flavonoid and chromone alkaloids but there has been some success in the synthesis of some of the compounds included in this category. 

The mechanism of flavonoid regulation of vacuolar biogenesis is not understood. However, the existence of vacuole biogenesis and flavonoid accumulation phenotypes in different mutants, such as mtv6, ahalO, ttl2, and tds4 [9, 10, 16,... 

The investigations on Populus have shown that there are several sites of flavonoid biogenesis Plastids, EE Unpublished results... 

These results suggest that the photo-oxidations may be models for the biogenesis of certein uncommon flavonoids, for example, compound A (31) (32), chaplasin (18) (30), and oxyisocyclointegrin (23) (31), which are supposedly derived in vivo from a 3-prenyl-2 -hydroxy... 

Biogenesis and Localization of Potymethylated Flavonoids in Cell Walls of Chrysosplenium americanum... 

Roux D G, Ferreira D 1974 a-Hydroxychalcones as intermediates in flavonoid biogenesis The significance of recent chemical analogies. Phytochemistry 13 2039-2048... 

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