Calorimetry, biochemical reactions

Since enthalpy changes can be obtained directly from measurement of heat absorption at constant pressure, even small values of AH for chemical and biochemical reactions can be measured using a micro-calorimeter.1112 Using the technique of pulsed acoustic calorimetry, changes during biochemical processes can be followed on a timescale of fractions of a millisecond. An example is the laser-induced dissociation of a carbon monoxide-myoglobin complex.13... 

Peters. K.S. and G.J. Snyder, Time-Resolved Photoacoustic Calorimetry Probing the Energetics and Dynamics of Fast Chemical and Biochemical Reactions, Science. 1053 (August 26, 1988). 

Calorimetry measurements are commonly utilized in biophysical and biochemical studies to determine energy changes as indications of biochemical reactions in a media [118]. Prior teclmiques for measurements include using electrodes, thermopiles, optical techniques, and microcalorimeters for measurements within a sampled media. 

The second volume in this series, edited by Skinner, treats many kinds of combustion calorimetry, fluorine reaction calorimetry, reaction calorimetry, high-temperature calorimetry, solution calorimetry, heats of mixing, microcalorimetry, and biochemical reactions. 

Petit, C.M. Koretke, K.K. Characterization of Streptococcus pneumoniae thymidylate kinase steady-state kinetics of the forward reaction and isothermal titration calorimetry. Biochem. J., 363, 825-831 (2002)... 

Calorimetry is not always practicable, especially for biochemically Important reactions, but in some cases their thermodynamic properties can be measured electrochemically. 

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