Bioceramics as Bone Substitutes

Bioceramics as Bone Substitutes The development of the so-called bioceramics is based on the knowledge that native bone is essentially composed of a more or less carbonated hydroxyapatite (HA) Caio(P04)(,(OH)2. With respect to the need for low solubility or of a controllable resorption, different compounds of the calcium phosphate system Ca(OH)2-H3P04-H20 have been applied for bone substitutes or bone fillings (Table 5.1). 

A good biocompatibility is observed for a Ca P ratio between 1 and 2, with an opti- 

Dicalcium phosphate (Bmshite) DCPD Ca(HP04)n2Hj0 1.00 1.87x10  

Dicalcium phosphate (anhydric) DCPA Ca(HP04) 1.00 1.26x10  

Carbon materials find widespread medical applications (Haubold et al. 1986) as ligament replacements (Amis etal. 1988  

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