Chick edema bioassay

Chick Edema Bioassay. Chick edema was produced in groups of birds treated with 1 and 10 /xg/kg/day of 2,3,7,8-TCDD and 10 and 100 /xg/kg/day of HCDD (Table V). The mean logarithm for pericardial fluid volume of the negative control groups was greater than 1.1460 and... 

Table V. Results of Chick Edema Bioassay Body Weight,...

Both 2,3,7,8-TCDD and HCDD give positive results in check edema bioassays (Table V). This HCDD result is consistent with a previous report that the HCDD isolated from pentachlorophenol produced chick edema (4). These same authors reported that 2,3,7,8-TCDD was extremely toxic in the chick embryo assay but did not report that it produced chick edema. 

---