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Binding of Bile Acids to Anion-Exchange Resins

Binding of Bile Acids to Anion-Exchange Resins [Pg.179]

There is evidence (18, 19) that the fraction of resin sites entering into mass-action equilibrium with the bile salt anions may not be constant but increases gradually as the concentration of the bile salt anions in the resin increases. The increase in binding could also indicate some form of a cooperative process. A possible explanation is that sodium cholate and sodium [Pg.180]

TABLE III. Recovery of 24-C Mabeled Bile Acids from Amberlyst XN-1006 (20)  [Pg.181]

Bile acid Amount added (cpm) Amount recovered (cpm) Percentage recovery [Pg.181]

Acids added at pH 11 to a 1 x 5 cm column of resin in the OH form. After washing with water and aqueous alcohol the bile acids were eluted with 150 ml of 0.2 M ammonium carbonate in 80% ethanol. The specific activity of the cholic, cheno-deoxycholic and deoxycholic acids was approximately 10, 8, and 3 /(c/mg, respectively. [Pg.181]


C. Binding of Bile Acids to Anion-Exchange Resins... [Pg.179]




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Acidic exchange resin

Acidic resin

Acidity exchange

Anion binding

Anion exchange

Anion exchange resin

Anion exchanger

Anion resins

Anionic exchange

Anionic exchangers

Anions anion exchange

Bile acid binding exchange resins

Bile acid binding resins

Bile acid resins

Bile acids binding

Binding, of anions

Exchange of anions

Exchangeable acidity

Resinic acids

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