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Binding and Metal-Based Anticancer Agents

Metal-Binding and Metal-Based Anticancer Agents [Pg.267]

While most drugs do not directly interact with endogenous metals, two clinically used antineoplastic agents are distinguished by this attribute bleomycin and doxorubicin. Metals also have a role in the treatment of cancer. The platinum-based antineoplastic agents, cw-diamminedichloro-platinum(II) (cisplatin) and cw-diamminedicarboxylatocyclobutaneplatinum [Pg.267]

B. Metal-Binding and Metal-Based Anticancer Agents... [Pg.267]

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Anticancer agents

Binding metallic

Metal agents

Metal-binding agent

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