Binder selection sugars

A patterned SAM, end-terminated with a binder to promote specific ligand attachment, can be used to localize cells, bacteria, yeast and polystyrene microspheres to a surface (29). A variety of binders are available to facilitate selective particle attachment, e.g. simple sugars, sialic acid containing gangliosides, lectins, RGD peptides and immunoglobulins have been reported. SAMs containing these receptors were discussed in the previous section. An alkane thiol derivative of a polysaccharide of glucose was prepared (29) and stamped in a... 

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