Binary kernel discrimination

Table 8 Mean Recalls at 5% for Similarity Searching (SS), Conventional Turbo Similarity Searching using Croup Fusion (TSS-CF) and Turbo Similarity Searching using Substructural Analysis (TSS-SSA) and Binary Kernel Discrimination (TSS-BKD)...

Harper G, Bradshaw J, Gittins JC, Green DVS, Leach AR. (2001) Prediction of Biological Activity for High-Throughput Screening Using Binary Kernel Discrimination. J. Chem. Inf. Comp. Set. 41 1295-1300. 

Chen B, Harrison RF, Pasupa K, Wilton DJ, WiUett P, Wood DJ, Delaney J, Lawson K, MuUier G. Evaluation of Binary Kernel Discrimination for Virtual Screening in Lead-Discovery Programmes. /. Chem. Inf Model, submitted for publication. 

Harper et al. have demonstrated a much better performance of probabilistic binary kernel discrimination method to screen large databases compared to... 

Many different methods can be applied to virtual screening, and such methods are described in other chapters of this book and/or in the Handbooks of Che-minformatics Here we discuss the methods based on a probabilistic approach. Unfortunately, there are many publications in which the probabilistic or statistical approach items are farfetched. The Binary Kernel Discrimination and the Bayesian Machine Learning Models are actually special... 

Harper, G., Bradshaw, J., Gittins, J.C., Green, D.V.S. and Leach, A.R. (2001) Prediction of biological activity for high-throughput screening using binary kernel discrimination./. Chem. Inf. Comput. Sci., 41, 1295-1300. 

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