Ligands binaphane

Fig. 2 f-Binaphane ligands 1. Summary of the best results obtained in the Ir-catalyzed hydrogenation of N-arylimines using la... 

Importantly, Zhang noted that the reaction did not proceed without the addition of iodine [10]. Furthermore use of Ti(OiPr)4 was not trivial, and replacement by MgSO4, 4 A MS, or TsOH was not helpful. They additionally noted that replacing the chiral /Binaphane ligand with BINAP or BIPHEP resulted in poor ee. The source of nitrogen is important because of the desire to ultimately provide a chiral primary amine screening studies with benzylamine, aniline, o anisidine, m anisidine, p anisidine, and 2,6 dimethylaniline showed p anisidine to be optimal. 

A variety of C2 symmetrical diphosphine ligands with a ferrocenyl backbone (see Fig. 25.5) have recently been described and tested, with sometimes quite impressive results. Interesting examples are f-binaphane [11], ferrotane [12], L2... 

The rhodium(I) complexes of the BINAP homologue, 2-diphenylphosphino-2 -diphenylphosphinomethyl-l,l -binaphthyl, that of the dinaphtho-phosphepino-benzene derivative (BINAPHANE) and bisbinaphthophosphepine ligand (BI-NAPINE), are active in enantioselective hydrogenation (203). The Rh-SEGPHOS systems catalyze the 1,4-addition of arylboronic acids (204). 

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