Biliverdin-9-dimethyl ester

S. E. Braslavsky, R. M. Ellul, R. G. Weiss, H.Al-Ekabi, K. Schaffner. Photoprocesses in Biliverdin Dimethyl Ester in Ethanol Studied by Laser-Induced Optoacoustic Spectroscopy (.LIOAS). Tetrahedron 1983, 39, 1909-1913. 

Figure 10. The origin of the contaminants responsible for the anomalous blue emission in phytochrome (A) and in the model compound biliverdin dimethyl ester (B) by the addition of a nucleophile at C(10) (A, X B, EtOH).

Photoprocesses in biliverdin dimethyl ester in ethanol have been studied by laser-induced optoacoustic spectroscopy." The picosecond kinetics of excited-state relaxation of this ester have also been reported." " Isophorcarubin is a conformationally restricted and highly fluorescent bilirubin." " The phototherapy for neonatal jaundice has stimulated investigations of configurational isomers of bilirubin" and of stereospecific and regioselective photoisomerization of bilirubin." ... 

Braslavsky, S.E., Ellul, R.M., Weiss, R.G., Al-Ekabi, H., and Schaffner, K. (1983) Pytochrome model 7 photoprocessesin biliverdin dimethyl ester in ethanol studied by laser-induced optoacoustic spectroscopy (LIOAS), Tetrahedron, 39, 1909-1913. 

Phytochrome Isolated bile pigments Biliverdin dimethyl ester Conformation ... 

Fig. 15. Absorption curve of biliverdin dimethyl ester in chloroform (138).

Biliverdine [114-25-0] M 582.6, m >300 , pK 3.0. This is the precursor of bilirubin (above) and forms dark green plates or prisms, with a violet reflection, from MeOH. The dimethyl ester, when crystallised from MeOH has m 215°(209°), and when ciystaUised from CHCl3/Pet ether gives blue-green crystals with m 202°. [Gray et al. J Chem Soc 2264 1961, Sheldiick J Chem Soc, Perkin Trans 2 1457 1976, Beilstein 26 III/V 3272.]... 

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