Dicyanodiamides biguanides

Brandimarte (Ref 3) describes the prepn of ASN, as follows PETN (20 parts) was added at 115-18° to a binary mixt of 70 ps AN and 10 ps dicyanodiamide, which had been previously fused for 6-8 hrs. The mixt was analyzed and found to contain ca 2% of GuN and ca 6% of biguanide nitrate, which were formed by interaction betw dicyanodiamide and AN... 

Phenylbiguanide-p-sulfonic acid is prepared by the usual reaction for the synthesis of Af-substituted biguanides the addition of dicyanodiamide (cyanoguanidine) to... 

Methods for preparation of dicyanodiamide involve polymerization of cyanamide under controlled conditions in aqueous solutions in the presence of metallic hydroxides or ammonia. Dicyanodiamide is an important chemical intermediate and is used for the preparation of guanidonium nitrate, biguanide, and numerous other derivatives of the ammonocarbonic acids. The present method is easily adaptable to preparation of laboratory quantities. 

---