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Betaine receptors

Zwitterionic receptors can be split into three classes (i) those that incorporate charge complementarity between the receptor and the zwitterions (ii) those in which the receptor binds one of fhe ionic parts of the substrate, which in turn causes a structural change (induced-fit) such that the other ion group then binds and (iii) betain receptors. Detains, for example, dioctanoyl-L-a-phosphaditylcholine (2.111), are nutrients that play a pivotal role in the cardiovascular system. Together with other nutrients, betains reduces the levels of toxic homocysteine (Hey) that may cause heart disease. Betains contain a tertiary trimethylammonium... [Pg.78]

Polycyclic compound 478, which forms stable complexes with urea, guanidine, amidines and their derivatives, is covered by patents (1991USP15030728, 1994USP5283333). These complexes were used in a biological investigation. Receptor betaine molecule 479 was constructed for diagnostic tests for blood (serum) creatinine and renal insufficiency. [Pg.270]

Respiratory More work addressing the genetic susceptibility to aspirin-intolerant asthma or aspirin-exacerbated respiratory disease has been published, implicating EMI domain-containing protein 2 [41, IV-acetyl transferase-2 [42, solute carrier family 6 (neurotransmitter transporter, betaine/ GABA) member 12 [43, prostaglandin E2 receptor 3 [44, and chemokine CC motif receptor 3 [45. ... [Pg.188]

Figure 44.1 Folate-mediated one carbon metabolism network. Enzymes and transport proteins are enclosed in rectangular boxes. AHCY S-adenosyDiomocys-teine hydrolase AICART 5-aminoimidazole carboxamide ribonucleotide transferase BHMT betaine homocysteine methyltransferase CBS cystathionine beta-synthase DHFR dihydrofolate reductase FR folate receptor FTCD formimidoyltransferase cyclodeaminase GART glycinamide ribonucleotide transformylase MATs (MATI/MATIII) adenosylmethionine transferase enzyme I/III MS methionine synthase MSR methionine synthase reductase MT methyltransferase MTHFD methylenetetrahydrofolate dehydrogenase MTHFR 5,10-methylenete-trahydrofolate reductase MTHFS 5,10-methylenetetrahydrofolate synthase. RFC reduced folate AdoMet 5-adenosylmethionine AdoHcy S-adenosylhomocysteine Hey homocysteine SHMT serine hydroxymethyltransferase TS thymidylate synthase. Figure 44.1 Folate-mediated one carbon metabolism network. Enzymes and transport proteins are enclosed in rectangular boxes. AHCY S-adenosyDiomocys-teine hydrolase AICART 5-aminoimidazole carboxamide ribonucleotide transferase BHMT betaine homocysteine methyltransferase CBS cystathionine beta-synthase DHFR dihydrofolate reductase FR folate receptor FTCD formimidoyltransferase cyclodeaminase GART glycinamide ribonucleotide transformylase MATs (MATI/MATIII) adenosylmethionine transferase enzyme I/III MS methionine synthase MSR methionine synthase reductase MT methyltransferase MTHFD methylenetetrahydrofolate dehydrogenase MTHFR 5,10-methylenete-trahydrofolate reductase MTHFS 5,10-methylenetetrahydrofolate synthase. RFC reduced folate AdoMet 5-adenosylmethionine AdoHcy S-adenosylhomocysteine Hey homocysteine SHMT serine hydroxymethyltransferase TS thymidylate synthase.
See other pages where Betaine receptors is mentioned: [Pg.1639]    [Pg.1644]    [Pg.1639]    [Pg.1644]    [Pg.100]    [Pg.177]    [Pg.96]    [Pg.467]    [Pg.266]    [Pg.168]    [Pg.300]    [Pg.1160]    [Pg.261]    [Pg.264]    [Pg.333]    [Pg.562]    [Pg.640]    [Pg.259]    [Pg.1644]    [Pg.79]    [Pg.1225]    [Pg.128]    [Pg.128]    [Pg.136]    [Pg.860]    [Pg.965]    [Pg.2064]   
See also in sourсe #XX -- [ Pg.1644 , Pg.1646 ]



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