Benzyl and Other Substituted Alkyl Ethers

Benzyl and Other Substituted Alkyl Ethers.—Phase-transfer catalysts have been used in the benzylation of such protected sugar derivatives as methyl 6-deoxy- 

3- ( -isopropylidene-a-L-mannopyranoside and in the monobenzylation of monosaccharide diols e.g. methyl 4,6-O-benzylidene-D-glucopyranosides), where the total yield of monobenzylated products may be substantially improved.  

The separation of fifteen O-benzyl ethers of methyl oc-o-glucopyranoside by g.l.c. of their TMS derivatives has been examined although neither the 2,3- and 

Benzyl 2,3,6-tri-O-benzyl-a-D-glucopyranoside and benzyl 6-0-allyl-2,4-di-O-benzyl-jS-D-galactopyranoside, which were required as intermediates in the 

Benzyl ethers have been used as temporary blocking groups in the synthesis of a blood-group H-specific trisaccharide, 2-acetamido-2-deoxy-4-0-(2-0-a-L-fucopyranosyl-j8-D-galactopyranosyl)-D-glucopyranose.  

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