2-benzoylphenyl

All applications with the exception of the two marked with a UV detection were obtained using MS detection. (5)-2-((2-Benzoylphenyl)amino)-3-(4-hydroxyphenyl)-propionic acid. 

The situation is different for alkylarylnitrenium ions. Haley first demonstrated that a A -l-adamantyl-A -(2-benzoylphenyl) nitrenium ion 62 (Fig. 13.36) could be generated by photolysis of an anthranilium ion." In this case, rearrangement of the adamantyl ring, to give products from hydrolysis of 63, competes with addition reactions, giving 64. Similar experiments carried out on A -tert-butyl-A -arylni-trenium ions also showed that the 1,2-shift of a methyl group competes with additions of nucleophiles to the aryl ring. In the latter cases, the formation of the alkylarylnitrenium ion was verified by LFP. 

Benzoylphenyl Tellurium Chloride1 In a dry, 100 m/ flask fitted with a reflux condenser topped with a drying tube are placed 6.5 g (20 mmol) of 2-carboxyphenyl phenyl tellurium, 5 ml (30 mmol) of butyl dichloromethyl ether, and 0.2 g (1.5 mmol) of anhydrous zinc chloride. The mixture is heated on a boiling water bath for 2 h, then diluted with carbon tetrachloride, charcoal is added, and the mixutre is filtered. The filtrate is evaporated to dryness and the residue is recrystallized from benzene/hexane yield 6.3 g (80%) m.p. 113-114°. 

Bis[2-benzoylphcnyl] Ditellurium [Potassium Hydroxide Method]3 To 200 ml of ethanolic potassium hydroxide are added 16.5 g (48 mmol) of 2-benzoylphenyl tellurium chloride and the mixture is heated until the reddish color disappears and potassium chloride precipitates. The mixture is poured into cold water and the ditellurium compound is extracted with chloroform. The extract is dried, evaporated to dryness, and the residue is recrystallized from benzene yield 12.3 g (83%) m.p. 139°. 

Benzoylphenyl Tellurium Cyanide2 An intimate mixture of 1.65 g (5 mmol) of 2-benzoylphenyl tellurium chloride and 1.5 g (10 mmol) of anhydrous silver cyanide is heated in an oil bath until the material has melted. The mixture is then allowed to cool to 20° and is extracted with chloroform. The chloroform extract is evaporated to dryness and the residue is recrystallized from hexane/benzene yield 1.3 g(80%) m.p. 135°. Similarly prepared was ... 

Vinyl A-(2-benzoylphenyl)-L tyrosine derivatives, (V), prepared by Jeppesen (5) were partial PPAR-a, PPAR-y, and PPAR-8 agonists and used in treating obesity, hyperglycemia, hyperlipidemia, and hypercholesterolemia. 

Hanson, P., Hammond, R. C., Gilbert, B. C., Timms, A. W. Sandmeyer reactions. Part 3. Estimation of absolute rate constants for the transfer of chloride ligands from Cull to 2-benzoylphenyl radical (Pschorr radical clock) and further investigations of the relative rates of transfer of chloride and water ligands to other substituted phenyl radicals. J. Chem. Soc., Perkin Trans, 21995, 2195-2202. 

Spirocyclic pyrido-l,3-oxazin-2-ones (277) can be obtained by the reactions of 2-amino-3-(l-hydroxycycloalkanyl)pyridines (276) with butyllithium and diethyl carbonate (Equation (26)) <89JHC113>, and l,4-dihydro-3,l-benzoxazin-2-ones (279) are available through the reactions of 2-benzoylphenyl isocyanates (278) with alcohols. The former are prepared by Friedel-Crafts acylation of benzene by 2-isocyanatobenzoyl chloride in the presence of aluminum(III) chloride (Scheme 81) and the whole process can be run as a one pot reaction <87JCR(S)96>. 

If the reaction is run in aqueous solutions, OH from the water can replace the halide as the aryl substituent, thus forming phenols 129). The reaction of the 2-benzoylphenyl radical to form the corresponding phenol is slower than the reaction forming the halo-aryl. The hydroxylation rate constant equals... 

Long-range C-C, C-N and N-N couplings in selectively labelled Ni(II) complexes of the Schiff base derived from (S)-iV-benzylproline(2-benzoylphenyl)am-ide and glycine have been measured by Popkov et al in CDCb solution. Their analysis provided evidence that the donation of electron density from the jt-system of the benzyl ring to the nickel orbitals takes place. 

The identification of pharmacophore and three-dimensional quantitative structure-activity studies were performed on a set of N-(2-Benzoylphenyl)-/-tyrosine for their PPARy agonistic activity by using the logic-structural-... 

C34H2oF620g, Tetraphenylferrole-iron tricarbonyl, 41B, 865 42B, 638 C3 4H2 OaPRe, (2-Benzoylphenyl)tricarbonyl(triphenylphosphine)-rhenium, 46B, 821... 

Benzoylphenyl)(2-hydroxyphenyl)methanone, 532 (2-Benzoylphenyl)(3-hydroxyphenyl)methanone, 533 (4-Hydroxy-l,3-phenylene)bis[phenylmethanone, 533 (5-Hydroxy-l,3-phenylene)bis[phenylmethanone, 529... 

Recently, Kawase developed a new synthesis for dibenzopentalene from an indenone derivative prepared by a novel amino-migration reaction. The reaction of 2,2 -dilithiotolan, generated from corresponding dibromide 284, with Af,Af-dimethylbenzamide produces 2-(2-benzoylphenyl)-3-phenylindenone 285 in 65% yield, the structure of which was determined by crystallographic analysis. The McMurry reaction of 287 subsequently leads to dibenzopentalene 256 in 58% yield (Scheme 6.71) [166]. 

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