Benzothiazoles 2,3-dihydro

Benzothiazole, 2-amino-6-thiocyanato-azo dyes from, 1, 328 Benzothiazole, 2-aryl-synthesis, 6, 321 Benzothiazole, 2-arylamino-synthesis, 6, 323 Benzothiazole, 2-aryloxy-Fries rearrangement, 6, 289 Benzothiazole, 2-benzyl-picrate, 6, 252 Benzothiazole, 2-chloro-dyes from, 1, 321-322 synthesis, 6, 323 Benzothiazole, 2,3-dihydro-oxidation, 6, 272 Benzothiazole, 2-dimethylamino-synthesis, 5, 128... 

Benzothiazole, 2-methyl-2-phenyl-2,3-dihydro-synthesis, 6, 325 Benzothiazole, 2-nitro-reactions, 6, 285 Benzothiazole, 5-nitro-nucleophilic attack, 5, 62 reactions... 

Diazadienes have been used in organic synthesis for the preparation of various heterocyclic compounds. Alkylation of 1,3-diazadienes 207 and the benz-fused analog 210 at the nitrogen atom by aryl acyl bromides provided the iV-alkyl amidinium bromides 208 and 211, which underwent annulation to the 2,3-dihydro-imidazo[2,l-A]thiazole 209 and imidazo[2,l- ]benzothiazoles 212, respectively (Equations 92 and 93) <2001S741, 2002J(P1)741>. 

Fig. 7 Structures of the dyes forming aggregates on DNA (a) l-methyI-4-[[3-methyl-2(3//)-benzothiazolylidene]methyl]-quinolinium (Thiazole Orange, TO), (b) 3,3 -diethyIthiadicarbo-cyanine (DiSC2(5)), (c) 3,3 -trimethylammoniopropylthiadicarbocyanine (DiSC3+(5)), (d) 2- [(Z)-2-(2,5-dihydro-2-thienyl)-3 - [3 -methyl-2(3/f)-benzothiazolylidene] -1 -propenyl] -3 -methyl -benzothiazol-3-ium (L-21), (e) 2-[( )-3-[3,7-diethyT6-[( ,2 )-3-(l-ethyl-3,3-dimethyl-3/7-indo-lium-2-yl)-2-propenylidene]-6,7-dihydrothiazolo[5,4-/]benzothiazol-2(3//)-ylidene]-l-propenyl]-l-ethyl-3,3-dimethyl-3//-indolium (BCD), (f) 3-methyl-2-[( )-3-methyl-2-[[3-methyl-2(3/f)-ben-zothiazolylidene]methyl]-l-butenyl]-benzothiazol-3-ium (Cyan ]3iPr)...

Carboxy-4,5-dihydro-I,3-thiazol-2-yl)-5- ( 4 -diazoniono-4-biphenylylazo)-6-hydroxy-1,3-benzothiazol-chlorid... 

Die elektrochemische, oxidative Kupplung von 2-Hydrazono-3-methyl-1,3-benzothiazol mit aromatisehen Aminen liefert 2-Arylazo-3-methyl-2,3-dihydro-1,3-benzothia-zole in 30% Ausbeute1 z.B, ... 

Dihydro allyl adducts like (254) are obtained by reaction of thiazoles with allyltributyl tin in the presence of alkyl chloroformates acting as activators of the thiazole ring (Scheme 28) (94JOC1319). This reaction most likely takes place via the intermediate azolium salt. Under these conditions even organolithium compounds can add to thiazoles (84TL3633). Similarly, direct ethynylation of thiazole and benzothiazole can be achieved by reaction with bis(tributylstannyl)acetylene (Scheme 29) (94SL557). 

In similar studies, the reduction potentials of 1,2-benzothiazole derivatives in DMF were correlated to antimycotic activity [166], and those of 1,3,5,7-substituted-1,3-dihydro-2H-l, 4-benzodiazepin-2-ones and benzodiazepine-2-thiones in dimethylformamide (DMF)-water solutions were correlated to inhibition of orientation reactions and to protection from electric shock [167]. 

Benzothiazin-4-ones, dihydro-synthesis, 3, 1028 Benzothiazole, acetoacetylamino-azo pigments from, 1, 334 Benzothiazole, 2-acyl-synthesis, 6, 265 Benzothiazole, 2-alkoxy-synthesis, 6, 323 Benzothiazole, 2-alkyl-synthesis, 6, 265 Benzothiazole, 2-alkyl-6-nitro-reactions... 

Nitration of 6-(benzothiazol-2-yl)-10-(4-methylpiperazin-l-yl)-9-fluoro-3(S)-methyl-2,3-dihydro- 7H-pyrido[l,2,3-cfe][l,4]benzoxazin-7-one with cone. HN03 in cone. H2SO4 gave 6-(6-nitrobenzothiazol-2-yl) derivative (09JMC5649). 

Dihydro-7-oxo-7//-pyrido[l,2,3-de]-l,4-benzothiazine-6-carboxylates (271) were obtained by the cyclization of a mixture of the E- and Z-iso-mers of acrylates 270 on the action of NaH in THF at 0°C (89GEP3913245 91SC2301 93EUP522277). Cyclization of aryl aminomethylenemalonates 272 in PPE at 130-145°C and on the action of Ph3P and ethyl azodicar-boxylate in THF at -20°C gave 7-oxo-2,3-dihydro-7//-pyrido[l,2,3-de]-l,4-benzothiazoles 273 (87USP4636506). 

An unsymmetrical cyanine dye for binding to the minor groove of DNA 4-[(3-methyl-6-(6-methyl-benzothiazol-2-yl)-2,3,-dihydro(benzo-l,3-thiaz-ole)-2-methyfidene)]-l-methyl-pyridinium iodide An isotherm for adsorption phenomena in chromatography acronym derived from Stephen Branauer, Paul Emmet, and Edward Teller Bound/free... 

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