Benzodiazepines brain damage

Baclofen, withdrawal syndrome, 26.152 Bambuterol, cardiac failure, 23.181 Benzodiazepines brain damage, 14.36 dependence, 12.41 depression, 17.43 medicolegal aspects, 13.33 Beta2-adrenoceptor agonists, 18.159 asthma, 19.178, 21.179 asthma deaths, 17.164 long-acting, respiratory adverse effects,... 

The role of benzodiazepines in brain damage has been reviewed (SEDA-14, 36). Cognitive impairment in longterm users can be detected in up to half of the subjects, compared with 16% of controls, but the issue of reversibility with prolonged abstinence is unresolved. Cognitive toxicity is more common with benzodiazepines than other anticonvulsants, with the possible exception of phenobar-bital (84). 

G.W. Price, R.G. Ahier, S.P. Hume, R. Myers, L. Manjil, J.E. Cremer, S.K. Luthra, C. Pascali, V. Pike, R.S.J. Frackowiak, In vivo binding to peripheral benzodiazepine binding sites in lesioned rat brain Comparison between [ H]PK11195 and f F] PK14105 as markers for neuronal damage, J. Neurochem. 55 (1990) 175-185. 

---