Benzodiazepine receptor antagonists specific agents

B. Specific drugs and antidotes. Flumazenil (see p 446) is a specific antagonist of benzodiazepine receptors. It does not appear to cross-react with other sedative agents. 

B. Specific drugs and antidotes. There are no specific antidotes. Flumazenll (see p 446) Is a specific antagonist of benzodiazepine receptors, and would not be expected to cross-react with skeletal muscle relaxants or other sedative agents. While physostigmine may reverse anticholinergic symptoms associated with cyclobenzaprine and orphenadrine overdose. It Is not generally needed and may potentially cause seizures. 

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