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Benzodiazepine antianxiety metabolism

The 1,5-benzodiazepine triflubazepam (ORF-8063, 19a) possessed antianxiety properties in man at 40-160 mg/day,54,55 with a profile similar to diazepam.56 Like most 1,4-benzodiazepines, it was primarily metabolized through N-dealkylation, but was otherwise hydroxylated in the N-phenyl ring rather than at C-3.57 Pharmacokinetic studies with... [Pg.5]

See other pages where Benzodiazepine antianxiety metabolism is mentioned: [Pg.277] [Pg.124] [Pg.406] [Pg.443] [Pg.1268] [Pg.277]

See also in sourсe #XX -- [ Pg.6 , Pg.533 , Pg.534 , Pg.535 ]

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Antianxiety

Benzodiazepine antianxiety