Benzimidazole 2-alkylthio

Tab. 25 2-Alkylthio- bzw. 2-Arylthio-benzimidazole durch Alkylierung bzw. Arylierung von 2-Mercapto-benzimidazolens a 372...

The fragmentation of isomeric 5- and 6-nitro-l-/Molucncsulfonyl-2-alkylbenzimida-zoles[695,710],S- 5(6)-nitrobenzimidazol-2-ylmethyl iV-morpholino-dithiocarbamate [1090], 4-, 5-, and 6-nitro-l-[)-A)-ribofuranosyl benzimidazole 3, 5 -phosphates [711], and the products of alkylation of 5(6)- and 4(7)-nitrobenzimidazole derivatives [702] has been studied. The molecular ion peaks of 2-alkylthio- and 2-ethylsulfono-5(6)-nitrobenzimidazole are reported [718],... 

FIGURE 11.83 Solid-phase synthesis of psoralen analogs. (From Song, A., Zhang, J., and Lam, K.S., Synthesis and reactions of 7-fluoro-4-methyl-6-nitro-2-oxo-27f-l-benzopyran-3-carboxylic acid a novel scaffold for combinatorial synthesis of coumarins, J. Comb. Chem., 6,112, 2004 Song, A. et al.. Solid-phase synthesis and spectral properties of 2-alkylthio-6//-pyrano[2,3-/ benzimidazole-6-ones a combinatorial approach for 2-aUcylthioimidazo coumarins, J. Comb. Chem., 6, 604, 2004 Song, A. and Lam, K.S., Parallel sohd-phase synthesis of 2-arylamino-6H-pyrano [2,3-f] benzimidazole-6-ones, Tetrahedron, 60, 8605, 2004.)... 

Song et al. [29] developed an efficient solid-phase approach for the S5mthesis of a series of novel psoralen analogs, 2-alkylthio-6H-pyrano[2,3-/]-benzimidazole-6-ones using Rink amide resins. The resins were bound to... 

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