Benzene derivatives hydroxyalkylation

In the reactions of various hydroxyalkyl-substituted benzene derivatives, which depend on the substituent attached to the phenyl ring, oxidation, ring fluorination. the addition process and substitution of a hydroxyalkyl group are all observed.22... 

Jorgensen and coworkers reported aluminum-mediated asymmetric hydroxyalkylation reaction of electron-rich benzene derivatives with 2-pyridinecarboxaldehyde... 

Strained cyclic ethers react with aromatic compounds with formation of hydroxyalkyl derivatives with ethylene oxide (oxirane) and aluminum chloride, benzene gives phenethyl alcohol in 70% yield,541 and with oxetane gives... 

Androstene and pregnane derivatives were reacted with syngas and some amino alcohols ([RhCl(NBD)]2 (NBD = norbornadiene), phosphine, CO/H2 = l l, 80 bar benzene) to afford the corresponding hydroxyalkyl/aryl compounds in yields of 70-93% as shown below (Figure 5.21) [89]. Monodentate phosphines, PBuj and PPhj, induced the highest yields of amines, whereas with DlOP as a ligand the multistep sequence stopped at the stage of the imine. Under all conditions, the diastereomeric a/p-ratio was close to 1. 

To improve rate performance, we have prep>ared cells containing a carbon layer on the current collector (CLC). This consists of a thin layer having a high concentration of conductive carbon material, situated between the activated carbon electrode layer and the current collector. We have foimd that a hydroxyalkylated chitosan (glycol-chitosan) derivative and 1,2,4,5-benzene-tetracarboxylic acid (pyromellitic acid) mixture acts as a thermally activated binder that adheres strongly to metal foil was very effective in improving the rate capability of EDLC cells. 

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