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Behavior, human executive functions

A PDE10A inhibitor may also have the potential to treat the cognitive symptoms of schizophrenia. The principal evidence for this claim is papaverine reversal of a PCP-induced deficit in the EDID-set shifting assay in rats [35]. This assay translates into human behavior in the form of the Wisconsin Card Sorting Test (WCST). EDID-set shifting is a test of executive function, a measure in which schizophrenics have a robust deficit. It has also been shown recently that papaverine is efficacious in the Novel Object Recognition cognition assay [36]. [Pg.9]

See other pages where Behavior, human executive functions is mentioned: [Pg.24]    [Pg.418]    [Pg.64]    [Pg.243]    [Pg.227]    [Pg.128]    [Pg.26]    [Pg.304]    [Pg.34]    [Pg.14]    [Pg.410]    [Pg.221]    [Pg.222]    [Pg.128]    [Pg.495]    [Pg.279]    [Pg.981]    [Pg.223]   
See also in sourсe #XX -- [ Pg.227 ]



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Executive function

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Human functions

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