Beads multicomponent polymer-based

This MFFD proved to be extremely versatile for the production of multicomponent polymer-based beads (Figure 18.9). By simply admixing the monomer phase with the appropriate reagent, Kumacheva and coworkers [14, 15] were able to incorporate dye, quantum dots and liquid crystals into poly(TPGDA) particles and to synthesize porous microspheres andalso copolymer particles madeofTGPAand acrylic acid (AA). 

Figure 18.9 Examples of multicomponent polymer-based beads synthesized in an MFFD polyfTPCDA) microspheres labeled with 4-amino-7-nitrobenzo-2-oxa-1,3-diazole dye (a) or CdSe quantum dots (b), polyfTPCDA) microspheres incorporating 4-cyano-4 -pentylbiphenyl liquid crystal as seen by...

Typically, a binary system was selected as the base component of the recipe and the addition of polyelectrolytes to either side (core or receiving bath) was tested to evaluate the change in the capsule properties. The 33 successful multicomponent membrane systems are presented in Table 1. The components of the core material side (21 different chemical compositions) are listed in the first column, while the receiving bath components (20 different chemical compositions) are listed in the second column. With the exception of xanthan and CMC, the first polymer listed on the core side are gelling polymers which form beads with the appropriate ionotropic cation (salt). CMC can also be gelled by ions (alum), although they are considered to be non-compatible for cellular applications. The cations were tested both sequentially, usually with ionotropic cation first, and simultaneously. Walled capsules with adequate mechanical properties were often obtained through the simultaneous application of two polycations. Such a... 

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