Bayliss effect

Myogenic control (also known as the Bayliss effect) of coronary artery tone occurs when the vessel is stretched secondary to an increase in pressure and contracts to return blood flow to normal. It is thought that the myogenic response to stretching in coronary arteries is a modest one and that metabolic factors such as nitric oxide play a much larger role in autoregulation. 

Bayliss, N.S. 1950. The effect of the electrostatic polarization of the solvent on the electronic absorption spectra in solution. J. Chem. Phys. 18 292-296. 

Bayliss, N. S. The Effect of the Electrostatic Polarization of the Solvent on Electronic Absorbtion Spectra. J. Chem. Phys. 18, 292 (1950). 

Woodroffe R, Yao G, Meads C, Bayliss S, Ready A, Raftery J, Taylor R. Clinical and cost-effectiveness of newer immunosuppressive regimens in renal transplantation a systematic review and modelling study. Health Technol Assess 2005 9(21) 1-194. 

A most comprehensive discussion of the effect of solvent on spectra has been given by Bayliss and McRae.21 They point out that polarization or dispersion forces are the most general interactions involved in solution and that all solution spectra are subject to a generalized polarization red shift, relative to vapor spectra, due to solvent polarization by the transition dipole. However, these dispersion forces are relatively weak and are easily obscured by the effect of dipole-dipole and dipole-static charge forces in polar, but not highly polarizable, solvents. By applying the Franck-Condon principle, they showed... 

Sirois, J. E., Lei, Q., Talley, E. M., Lynch III, C., Bayliss, D. A. The TASK-1 two-pore domain fC channel is a molecular substrate for neuronal effects of inhalational anesthetics, The Journal of Neuroscience 2000, 20, 6347-6354. 

Since Bayliss wrote these paragraphs, Lapicque has shown that curare changes the chronaxie of the muscle, thereby throwing it out of step with the nerves. It is a blocking effect and not a complete paralysis of the muscle. 

Urban P Buller N, Fox K, Shapiro L, Bayliss J, Rickards A. Lack of effect of warfarin on the restenosis rate or on clinical outcome after balloon coronary angioplasty. Br Heart J 1988 60(6) 485-488. 

Bayliss DA, Li YW, Talley EM. Effects of serotonin on caudal raphe neurons Activation of an inwardly rectifying potassium conductance. J Neurophysiol 1997 77 1349-1361. 

Bayliss, N.S. and Wills-Johnson G., Solvent effects on the intensities and weak ultraviolet spectra of ketones and nitroparaffins -1. Spectrochim. Acta (1968) 24A 551-661. 

In strong acid solution there is much physical evidence for the existence of NO (Bayliss et al., 1963) and its salts are well known. It has been argued for lower acidities [where reaction occurs according to (6)] that the concentration of NO is too low to effect reaction, so the nitrous acidium ion has been proposed as the effective reagent. Although there is no physical evidence for the existence of HaNOJ, it may well be involved. The detailed case for and against involvement in reactions in dilute acid has been presented... 

A similar analysis is made for the case of benzene in water. This interesting system is considered stimulated by nice experimental results for the spectral shifts obtained by Bayliss and Hulme(6). Possible hydrophobic effects are not identified nor discussed by Bayliss but it is under current investigation in our group. 

Although the action of barbiturates on the biosynthetic chain to at least two phospholipids is apparently at a point subsequent to the phosphorylation of the base, an investigation of later stages (Fig. 2) proved difficult because of the low concentration of the cytidine nucleotides in the brain (Nelson and Barnum, 1960 Ansell and Bayliss, 1961). This investigation should be possible in vitro and has been carried out for chlorpromazine (Section III, B). Although no experiments have apparently been carried out on the effect of barbiturates on the biosynthesis of cytidine nucleotides in vitro, studies have been made on the transfer of P 2-orthophosphate to phospholipids. This transfer presumably involves cytidine nucleotides for certain phospholipids. Strickland (1954) found that 4 X 10 M Chloretone (l,l,l-trichloro-2-methyl-2-pro-... 

Donnan showed from thermodynamic considerations that there may be different concentrations of a freely diffusible salt in equilibrium on two sides of a membrane if a salt (e.g. the sodium salt of Congo red) is present on one side, an ion of which does not pass through the membrane. The effect enters into the osmotic pressure of such solutions, and an electrical potential difference between the two sides of the membrane was verified by Donnan and G. M. Green. W. M. Bayliss had discovered the effect experimentally with the osmotic pressure of Congo red, and its importance in physiology was demonstrated by J. Loeb. ... 

N. S, Bayliss and E, G. McRae, / Phys, Chem., 58, 1006 (1954). Solvent Effects in Organic Spectra of Acetone, Crotonaldehyde, Nitromethane and Nitrobenzene. 

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