Bayer Timed-Release

Tablets, timed-release 650 mg (ofc) 8-hour Bayer Timed-Release Caplets (Glenbrook)...

A.S.A., A.S.A. Enseals, Ascriptin, Aspergum, Bayer Timed-Release, Bufferin, Buffinol, Easpirin, Ecotrin, Empirin, Encaprin, Entrophen, Measurin, Zorprin)... 

As mentioned before, nifedipine was the first marketed dihydropyridine CCB. Initially, the drug indication was exclusively for angina, but the more recently developed extended release (ER) formulations are used off-label primarily for hypertension (Bayer, 2004). The extended-release tablets use a cellulose coat that extends their release time. The half-life of the ER formulation is reported as 7 h, whereas the immediate-release formulation has a half-life of 2 h (Bayer). 

Only after o-phthalodinitrile became available in high purity on an industrial scale from BASF the importance of these pigments was recognized. By improving the methods of synthesis and finishing it became possible to produce pigments with brilliant hues and better fastness properties. In 1973 BASF released the first isoindoline pigment into the market Lithol Fast Yellow 1840 (P.Y. 139). At the same time several other companies (Bayer, Ciba, Dainippon Ink) published novel isoindoline structures [8- 11]. 

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