Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Basiliximab, organ transplant monoclonal

Anticytokine receptor antibodies Basiliximab, Da-cluzimab Both are humanized monoclonal antibodies against the IL-2 receptor that block T-cell proliferation by inhibiting IL-2 and thus decrease the T-cell mediated frequency of rejection episodes in organ transplantation. [Pg.617]

Basiliximab is a mouse/human chimeric monoclonal antibody with specificity and high affinity for the a-subunit of the IL-2 receptor. The antibody acts as an lL-2Ra antagonist and inhibits lL-2-mediated activation and proliferation of T l)unphocytes. It is indicated for the prevention of acute organ rejection in adult and paediatric renal transplant recipients in combination with other immunosuppressive agents like cyclosporin, azathioprine, mycophenolate mofetU... [Pg.61]

See other pages where Basiliximab, organ transplant monoclonal is mentioned: [Pg.87]    [Pg.1200]    [Pg.87]    [Pg.311]    [Pg.87]    [Pg.181]   


SEARCH



Basiliximab

Organ transplantation

Transplanted organ

© 2024 chempedia.info