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Bactobolin antitumor antibiotic

SES-NSO also reacts with ketones in the presence of Lewis acids and the resulting iV-sulfonylimines can be reduced to the corresponding sulfonamides with NaBH3CN (eq 3). Such a reaction sequence has been employed in a synthesis of the antitumor antibiotic (—)-bactobolin. ... [Pg.609]

In a total synthesis of the antitumor antibiotic (—)-bactobolin (18), the choice of protecting group on the nitrogen was crucial (eq 10). Unlike other protecting groups, the SES group is compatible with a wide variety of transformations and reagents, and is easily removed at the end of the synthesis. [Pg.612]

See other pages where Bactobolin antitumor antibiotic is mentioned: [Pg.157]    [Pg.189]   
See also in sourсe #XX -- [ Pg.3 , Pg.16 ]

See also in sourсe #XX -- [ Pg.3 , Pg.16 ]



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Antitumor antibiotic

Bactobolin

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