Bacterium Streptomyces griseus

Fredericamycin is a curious aromatic compound extracted in 1981 from the soil bacterium Streptomyces griseus. It is a powerful antibiotic and antitumour agent, and its structure is shown below. The first time it was made in the laboratory, in 1988, the chemists in Boston started their synthesis with three consecutive lithiation reactions two are ortholithiations, and the third is slightly different. You needn t be concerned about the reagents that react with the organolithiums just look at the lithiation reactions... 

Streptomycin is also an aminoglycoside antibiotic that is soluble in water. It is obtained from Streptomyces griseus bacterium. There are 15 chiral centers in this molecule and no cavity. It has one pyranose and one furanose ring, six hydroxyl groups, two primary amine groups, and four secondary amine groups. This arrangement makes the molecule stereo-specific in nature. 

Vertebrates, invertebrates, Streptomyces griseus and the soil bacterium, Myxobacter 495,... 

Yeast-glucose medium Streptomyces Griseus No. 3570 bacterium... 

Several investigations were carried out to remove toxic heavy metal ions from waste water by biosorption. Microbial cells loaded with heavy metals were recovered by flotation, e.g. Streptomyces griseus and S clavuUgerus loaded with Pb [108] and Streptomyces pilosus loaded with Cd [109]. In these flotation processes the microbial cells were dead therefore, they are not considered here. The removal of pyritic sulfur from coal slurries such as coal/water mixtures by Thiobacillus ferrooxidans and recovery of this iron-oxidizing bacterium by flotation is a special technique in the presence of high concentrations of solid particles (see e.g. [110]). The flotation of colloid gas aphrons was used for the recovery of yeast in continuous operation [ 111 ] for the recovery of micro algae, and in the presence of flocculants in batch operation [112]. These special techniques are not discussed here. 

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