Bactericidal, definition

Clofazimine is a substituted iminophenazine that was first proposed for treating leprosy in 1962 however, it entered into medical practice toward the end of the 1980s. The mechanisms of its action is not definitively known, although there is the assumption that it can inhibit the formation of matrixes with DNA, which leads to a delay in the growth of mycobacteria. Clofazimine exhibits a bactericidal effect between that of dapsone and rifampicin. Synonym of this drug is lamprene. 

In the group of synthetic benzofurans are found nitro derivatives with the nitro group on the benzofuran ring.36-38 It is difficult to attribute these properties to a definite toxophore, isopropyl derivatives being at least as active as nitro derivatives. Nitrobenzofurans are also bactericidal.39,40 A parallel between structure and antibacterial activity has been made in the nitrofuran series.41... 

CAS 94-18-8 EINECS/ELINCS 202-311-9 Synonyms Benzoic acid, 4-hydroxy-, phenyl methyl ester Benzyl 4-hydroxybenzoate Benzyl p-hydroxybenzoate Phenylmethyl 4-hydroxybenzoate Definition Ester of benzyl alcohol and p-hydroxybenzoic acid Empirical C14H12O3 Toxicology TSCA listed Uses Preservative, bactericide, fungicide for foods, pharmaceuticals, industrial applies. antimicrobial in cosmetics Regulatory BP compliance Manuf./Distrib. Aldrich http //www.sigma-aldrich.com-, Alfa Aesar http //www.aifa.com-, Archimica Inc http //www.archimica.com-. 

Definition Extract derived from Cinchona spp. Uses Natural flavoring agent in foods medicine (analgesic, anesthetic, antibacterial, antimalarial, antimicrobial, antipyretic, astringent, bactericide, fungicide, febrifuge. 

Definition Extract of the lichen, Usnea barbata Uses Botanical, deodorant agent in cosmetics preservative, natural bactericide, fungicide for deodorants, liq. soaps, creams, lotions... 

Introduction - Cranplement was discovered in the late nineteenth century %fhen it was recognized that the bactericidal activity of fresh serum required the participation of at least two factors a heat-stable factor, specific for the particular organism (antibody) and a second, non-specific, heat-labile factor designated complement. During the two decades following the discovery of complement, it became apparent that complement did, in fact, consist of several components which act in a definite sequence to effect lysis and death of the bacteria. In the 1950 s, the development of sophisticated methods in protein chemistry and suited>le functional assays for Individual complement components facilitated the elucidation of the chemical, physical, and functional properties of the complement system. 

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