Azides, 149 Curtiss

In the first synthesis [50] phenol (150) prepared from dehydroabietic acid as starting material [51] and this was converted to trifluoroacetate (151). The azide (152) prepared from (151), underwent Curtis rearrangement yielding isocyanate (153). Reduction of (153) followed by heating the resulting material with formic acid and formaldehyde provided the tertiary amine (154). Its conversion to ketone (155) was accomplished in three steps (a) oxidation with m-cloroperbenzoic acid, (b) Cope elimination and (c) oxidative cleavage. [Pg.203]

Cyanogen bromide, triazine method, cychc trani-2,3-carbonate reaction, carbonylation, periodate oxidation, epoxide activation Curtis azide rearrangement, coupling reagent method, acid anhydride reaction Schiff base formation reaction... [Pg.40]

FIGURE 3.14 Schematic representation of (a) Curtis azide activation and (b) coupling reagents activation method. [Pg.42]

The Curtis Reaction Lysergic Acid Hydrazine Lysergic Acid Azide and Lysergic Acid Amides... [Pg.51]

Carboxyl Poly(acrylic acid), poly(glutamic acid), CM-cellulose, poly(acryl amide) Curtis azide rearrangement, coupling reagents method, acid anhydride reaction [182-185]... [Pg.119]