Axinyssa fenestratus

In a recent study, a Fijian sponge, Axinyssa fenestratus, was found to elaborate four isothiocyanatoamorphanes (43-46) [45]. That this series of compounds may be antipodal to 32 from the Hawaiian Halichondria sp. was indicated by the spectral and optical data of 43 [(1 R,6S,1S, 1 OS)- 10-isocyanato-4-amorphene]. 

Three new antiparasitic sesquiterpene isothiocyanates, 4-isothiocyanato-9-amorphene (264), 10-isothiocyanato-4,6-amorphadiene (265) and 10-isothiocyanato-5-amorphen-4-ol (266) were isolated from a Fijian specimen of Axinyssa fenestratus. The compounds were identified by spectral data interpretation [268]. Two isomeric isothiocyanates (267-268) were isolated from Acanthella klethra from the Great Barrier Reef and their structures were determined by X-ray crystallography and spectral data examination [269]. 

IR,6S, 7S,10S)-10-isothiocyanato-4-amorphene Axinyssa fenestratus [168] Anthelmintic activity... 

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