Axinella damicornis

Few of the novel fungal products that have been discovered contain the pyrrole ring as distinguishing structural feature. Of chemical interest is the metabolite 68 from the ethyl acetate extract of a static culture of Aspergillus niger isolated from the Mediterranean sponge Axinella damicornis, which contains the hitherto unprecedented pyrano[3,2- ]pyrrole skeleton <2004JNP1532>. 

Costantino, V., D Esposito, M., Fattorusso, E., Mangoni, A., Basilico, N., Parapini, S., and Taramelli, D. (2005a) Damicoside from Axinella damicornis the influence of a glycosylated galactose 4-0 H on the immunostimulatory activity of a-galactoglycosphingolipids. J. Med. Chem., 48, 7411-7417. 

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