Auxin genetic approaches

A number of investigators have taken a genetic approach to the identification of genes and proteins involved in auxin response, particularly in Arabidopsis [47]. The sensitivity of Arabidopsis seedlings to low concentrations of exogenous auxin has been the basis for extensive screens for auxin response mutants. At least nine genes have been defined in these screens and four have been characterized at the molecular level (Table 1). The product of the AUXl gene probably functions in cellular auxin influx and will not be discussed further here [56]. 

Hobbie, L. and M. Estelle Genetic approaches to auxin action Plant Cell Environ. 17 (1994) 525-540. 

The final example of our chemical genetic approach to dissect herbicide action involves auxin biology. A subset of our bioactive compound library that exhibited auxinic herbicidal symptoms was tested for inhibition of root growth of Arabidopsis seedlings. The most potent of these compounds was a novel picolinate auxin DAS534. Previous mutational studies with 2,4-D have elucidated an auxin signal-... 

A Genetic Approach to Auxins and Cytokinins Relative growth (% control)... 

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