Atrial fibrillation clinical significance

Oral H, Knight BP, Ozaydin M, et al. Clinical significance of early recurrences of atrial fibrillation after pulmonary vein isolation. J Am Coll Cardiol 2002 40 100-4. 

Chugh A, Oral H, Lemola K, et al. Prevalence, mechanisms, and clinical significance of macroreentrant atrial tachycardia during and following left atrial ablation for atrial fibrillation. 

The clinical consequences of significant mitral regurgitation are numerous and include impaired quality of life (particularly with dyspnea and fatigue on exertion), left ventricular enlargement and dysfunction, arrhythmias such as atrial fibrillation, secondary pulmonary hypertension and sudden cardiac death. Concomitant mitral regurgitation can be particularly deleterious in patients with either congestive heart failure or ischemic heart disease (15,16). 

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