Atopic syndrome atopy

Most genuine allergic diseases seen in the majority of practices are due to IgE-mediated sensitivity and are related to the atopic syndrome. Atopy... 

Low levels of IgE production are a normal part of the spectrum of antibody responses in most species, although some strains of experimental animals and atopic humans have a genetic propensity to produce proportionally greater amounts of IgE. Normal individuals will produce large amounts of specific IgE-class antibody in response to stimuli such as parasitic infection. Although raised total serum levels of IgE are seen in atopies as a group, this correlates better with the presence and activity of eczema than with the other manifestations of the syndrome (Johansson et al, 1970). 

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