Salbutamol Atomoxetine

ATOMOXETINE BRONCHODILATORS -SALBUTAMOL t risk of arrhythmias with parenteral salbutamol Additive effect Avoid co-administration of atomoxetine with parenteral salbutamol... 

The manufacturer contraindicates the concurrent use of atomoxetine and MAOIs on theoreticai grounds. Atomoxetine is predicted to have additive effects with pressor drugs and other sympathomimetics and has been seen to potentiate the increase in heart rate and biood pressure seen with intravenous salbutamol. However, no increase in cardiovascuiar effects was seen when atomoxetine was given with methyiphenidate. 

The manufacturer notes that atomoxetine 60 mg twice daily for 5 days potentiated the increase in heart rate and blood pressure caused by an infusion of salbutamol 600 micrograms over 2 hours. Because of this, they recommend caution when atomoxetine is used in patients receiving intravenous or oral salbutamol or other beta2 agonists (for a list, see Table 33. r, (p.ll59)). The UK manufacturer also extends this precaution to high-dose nebulised salbutamol. ... 

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See also in sourсe #XX -- [ ]

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