Chromatin atomic force microscopy

Figure 4. Visualization of PARP-1-mediated chromatin compaction by atomic force microscopy. Chromatin assembled in vitro on a circular 10.5kb plasmid DNA was purified, incubated widi or without recombinant human PARP-1, and imaged by atomic force microscopy. Two types of images are shown scan probe oscillation amplitude (top) and topography (bottom height scale is indicated). The length scale is indicated. (See Colour Plate 6.)...

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