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Ketanserin Atenolol

The role of serotonin (5-HT) in the cardiovascular system is also an active subject of investigation. Synthesis of the thiophene isosteres of ketanserin shows that the thieno[3,2- /] isomer (39) is 4-fold more selective for 5-HT2 vs. 5-HTia or a receptors than is ketanserin <91EJM807>. Tibalosine (CP 804 S, (40)) is a highly selective a 1-adrenoceptor antagonist which is significantly less potent than prazosin <83MI 212-01 >. Compound (41) is more than 100 times more selective than atenolol... [Pg.686]

There is no pharmacokinetic interaction between ketanserin and propranolol, but additive hypotensive effects may occur. Very marked acute hypotension has been seen in two patients taking atenolol when they were first given ketanserin. [Pg.894]

Acute hypotension is reported to have occurred in two patients taking atenolol within an hour of taking a 40-mg oral dose of ketanserin. One of them briefly lost consciousness. ... [Pg.894]

See other pages where Ketanserin Atenolol is mentioned: [Pg.45]    [Pg.82]    [Pg.345]    [Pg.501]    [Pg.906]    [Pg.1025]    [Pg.1183]    [Pg.1199]    [Pg.1221]    [Pg.1304]    [Pg.1319]    [Pg.1366]    [Pg.1380]    [Pg.1463]    [Pg.45]    [Pg.501]    [Pg.906]    [Pg.1025]    [Pg.1183]    [Pg.1199]    [Pg.1221]    [Pg.1304]    [Pg.1319]    [Pg.1366]    [Pg.1380]    [Pg.1463]   
See also in sourсe #XX -- [ Pg.894 ]



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Ketanserin

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