Atacand - Candesartan cilexetil

Atacand (Candesartan cilexetil). AstraZeneca. US Prescribir infwTiiation, February 2007. [Pg.37]

USAN Candesartan cilexetil Trade name Atacand ... [Pg.129]

Angiotensin II receptor antagonists, such as losartan (Cozaar, Hyzaar), valsartan (Diovan), irbesartan (Avapro), and candesartan cilexetil (Atacand). [Pg.48]

Candesartan cilexetil (Atacand) This cilexetil is an inactive ester prodrug that is completely hydrolyzed to the active form, candesartan, during absorption from the gastrointestinal tract. Peak plasma levels are obtained 3 to 4 hours after oral administration, and plasma half-hfe is about 9 hours. Plasma clearance of candesartan is due to renal elimination (33%) and biliary excretion (67%). Candesartan cilexetil should by administered orally once or twice daily for a total daily dosage of 4 to 32 mg. [Pg.128]

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