Asymmetric transformation of ketone

The DKR processes for secondary alcohols and primary amines can be slightly modified for applications in the asymmetric transformations of ketones, enol esters, and ketoximes. The key point here is that racemization catalysts used in the DKR can also catalyze the hydrogenation of ketones, enol esters, and ketoximes. Thus, the DKR procedures need a reducing agent as additional additive to enable asymmetric transformations. 

Asymmetric reductive acetylation process was also applicable to acetox-yaryl ketones. For example, m-acetoxyacetophenone 10 was transformed to 

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J. Park, Practical ruthenium/lipase-catalyzed asymmetric transformations of ketones and enol acetates to chiral acetates,... 

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